The development of DNA sensor systems is of great importance for advances in medical science. Now another piece of the puzzle for the development of personalized medicine has been found with the results of a highly sensitive monitoring of cancer-related topoisomerase II enzymes.
When chemically modified, this 'alginate' reduces oxidative stress, has an anti-inflammatory effect in cell culture tests and suppresses the immune reaction against cartilage cells, thereby combating the causes of arthritis.
A new data analysis technique, moving subtrajectory analysis, defines the dynamics and kinetics of key molecules in the immune response to an infection. These biophysical descriptions are expected to clarify the TCR microcluster, an essential assembly for a T cell to initiate its attack on a pathogen.
The collagen changes its crystallinity in response to physical forces, so the ordered arrangement in collagen molecules of the cartilage in our knees may be flipping from one structural state to another with every step we take.
By employing molecular biology tools, a team of researchers measured the way mercury affects the gene expression of algae, even when its concentration in water is very low, comparable to European environmental protection standards.
New research results may lead to new drugs that could promote hair growth for people with baldness or alopecia, which is hair loss associated with such factors as hormonal imbalance, stress, aging or chemotherapy treatment.