Using cryo-electron microscopy (cryo-EM), scientists have made a significant breakthrough in our understanding of how our molecular machinery finds the right DNA to copy, showing with unprecedented detail the role of a powerhouse transcription factor known as TFIID.
Scientists develop novel way to inject healthy human nerve cells into the brain. The technology involves converting adult tissue-derived stem cells into human neurons on 3-D scaffolds, or tiny islands, of fibers.
Scientists have developed a 3D micro-scaffold technology that promotes reprogramming of stem cells into neurons, and supports growth of neuronal connections capable of transmitting electrical signals. The injection of these networks of functioning human neural cells - compared to injecting individual cells - dramatically improved their survival following transplantation into mouse brains.
Remember those colorful 'grow capsules' that blossom into animal-shaped sponges in water? Using a similar idea, scientists have developed biodegradable polymer grafts that, when surgically placed in damaged vertebrae, should grow to be just the right size and shape to fix the spinal column.