With the first detailed analysis of a cellular component from a close relative of the pathogen that causes tuberculosis, scientists are suggesting strategies for new drugs to curb this growing health problem.
Researchers created a new bacterium that uses the four natural bases (called A, T, C and G), which every living organism possesses, but that also holds as a pair two synthetic bases called X and Y in its genetic code.
Many vaccines contain viruses that are inactivated to prevent them from harming recipients. This is generally achieved by adding chemicals. Now scientists are taking a different approach, using low-energy-electrons to irradiate the pathogens. The advantages of this new method are that it produces no toxic waste and provides a faster and less aggressive way of rendering pathogens inactive.
A new type of adhesive that combines the bonding chemistry of shellfish with a bio-based polymer has been shown to perform as well as commercially available products and can be easily degraded, representing a potential non-toxic alternative.
Scientists have developed a model that can be used to assess emerging synthetic biology products, well before they are ready for the market, to determine what needs to be done to inform future policies.
Researchers have developed a method that makes it possible to see how individual molecules from solvents in skin creams, medicated ointments and cleaning products affect and interact with the skin's own molecules.
Chemical engineers have genetically reprogrammed a strain of yeast so that it converts sugars to fats much more efficiently, an advance that could make possible the renewable production of high-energy fuels such as diesel.
Using a combination of infrared spectroscopy and computer simulation, researchers have gained new insights into the workings of protein switches. With high temporal and spatial resolution, they verified that a magnesium atom contributes significantly to switching the so-called G-proteins on and off.
Researchers have developed a multiregional brain-on-a-chip that models the connectivity between three distinct regions of the brain. The in vitro model was used to extensively characterize the differences between neurons from different regions of the brain and to mimic the system's connectivity.