New research demonstrates a new technology advancing the field of genome engineering. The method significantly improves the ability of scientists to target specific faulty genes, and then 'edit' them, replacing the damaged genetic code with healthy DNA.
A new study defines the core set of genes and functions that a bacterial cell needs to sustain life. The research, which answers the fundamental question of what minimum set of functions bacterial cells require to survive, could lead to new cell engineering approaches for E. coli and other microorganisms.
Using photosynthetically active microorganisms, researchers have succeeded in manufacturing several biocatalysts suitable for industrial application: a crucial step towards sustainable chemical processes.
New research suggests active biological mechanisms transport scent and taste compounds known as volatiles from plant cells to the atmosphere, a finding that could overturn the textbook model of volatile emission as a process that occurs solely by diffusion.
Scientists have developed artificial blood vessels that are not susceptible to blood clot formation. The achievement was made possible by a new generation of drug-containing coating applied to the inner surface of the vessel.
The ability to visualize and characterize the composition of a tumour in detail during its development can provide valuable insights in order to target appropriate therapeutics. Researchers now have visualized and quantified the growth and composition of breast tumours over time in a living animal.
Researchers have engineered a tethered ribosome that works nearly as well as the authentic cellular component, or organelle, that produces all the proteins and enzymes within the cell. The engineered ribosome may enable the production of new drugs and next-generation biomaterials and lead to a better understanding of how ribosomes function.
A new technology will dramatically enhance investigations of epigenomes, the machinery that turns on and off genes and a very prominent field of study in diseases such as stem cell differentiation, inflammation and cancer.