Researchers have demonstrated that when exposed to repeated cycles of antibiotics, within days bacteria can evolve a new adaptation, by remaining dormant for the treatment period to survive antibiotic stress. The results show for the first time that bacteria can develop a biological timer to survive antibiotic exposure. With this new understanding, scientists could develop new approaches for slowing the evolution of antibiotic resistance.
By labelling the ends of thousands of microtubules, which are indispensable and extremely dynamic and variable, researchers have finally been able to follow their distribution and movement during the assembly of the mitotic spindle.
With the plethora of research and published studies on stem cells over the last decade, many would say that the definition of stem cells is well established and commonly agreed upon. However, a new review article suggests that scientists have only scratched the surface of understanding the nature, physiology and location of these cells.
Researchers have developed new methods to trace the life history of individual cells back to their origins in the fertilised egg. By looking at the copy of the human genome present in healthy cells, they were able to build a picture of each cell's development from the early embryo on its journey to become part of an adult organ.
Scientists have found a 'Trojan horse' way to deliver proteins into live human cells without damaging them. The finding is expected to be easily adopted for use in medical research to find cures and treatments for a wide range of diseases.
Scientists are reporting the next step in the evolution of wound treatment with a material that leads to faster healing than existing commercial dressings and prevents potentially harmful bacteria from sticking.
This review article summarizes the structure and stability of all the minichromosomes that Minoru Murata and colleagues at Okayama University have isolated since 2006, and describes their interesting features.
Trillions of bacteria live in the human body, and although there's plenty of evidence that these microbes play a collective role in human health, we know very little about the individual bacterial species. Employing the use of a specially designed glass chip with tiny compartments, researchers provide a way to target and grow specific microbes from the gut - a key step in understanding which bacteria are helpful to human health and which are harmful.
Researchers gained new insight into the role of CCL2, a chemokine known to be involved in the immune response, in the enhancement of stem cell pluripotency. In the study, the researchers replaced basic fibroblast growth factor (bFGF), a critical component of human stem cell culture, with CCL2 and studied its effect.