Scientists from Karolinska Institutet in Sweden have made progress in understanding how human genes are regulated. In their study they have identified the DNA sequences, which bound to over four hundred proteins controlling the expression of genes.
In biology, molecules can have multi-way interactions within cells, and until recently, computational analysis of these links has been "incomplete," according to T. M. Murali, associate professor of computer science in the College of Engineering at Virginia Tech. His group authored an article on their new approach to address these shortcomings.
After years of experimentation, researchers at the University of Arkansas have solved a complex, decades-old problem in membrane biochemistry. The consequence of their work will give scientists more information about the function and structure of proteins, the workhorses within the cells of the human body.
With projections of 9.5 billion people by 2050, humankind faces the challenge of feeding modern diets to additional mouths while using the same amounts of water, fertilizer and arable land as today. Cornell researchers have taken a leap toward meeting those needs by discovering a gene that could lead to new varieties of staple crops with 50 percent higher yields.
Scientists at the SUNY College of Environmental Science and Forestry (ESF) are developing a biochemical process that uses a protein molecule to disrupt the process by which bacteria become virulent, a finding that could have widespread implications for human health.
While working out the structure of a cell-killing protein produced by some strains of the bacterium Enterococcus faecalis, researchers stumbled on a bit of unusual biochemistry. They found that a single enzyme helps form distinctly different, three-dimensional ring structures in the protein, one of which had never been observed before.
A new metabolic engineering tool that allows fine control of gene expression level by employing synthetic small regulatory RNAs was developed to efficiently construct microbial cell factories producing desired chemicals and materials.
Scientists at the Research Institute of Molecular Pathology (IMP) in Vienna, Austria and at the University of Cologne, Germany have discovered the molecular basis underlying the patterned folding and assembly of muscle proteins.
Genes make up only a minority of the entire genome sequence - roughly two percent in humans. The remainder was once dismissed as "junk", mostly because its function remained elusive. "Dark matter" might be more appropriate, but gradually light is being shed on this part of the genome, too.
Fraunhofer researchers are exhibiting how renewable, biodegradable and biostable raw materials can be used in architecture, interior design and the packaging industry at this year's International Green Week in Berlin.