Researchers have created a hydrogel scaffold replicating the environment found within the human breast. The scaffold supports the growth of human mammary tissue from patient-derived cells and can be used to study normal breast development as well as breast cancer initiation and progression.
Researchers have shown that there is an anti-correlation between the number of aggregation prone regions (APRs) in a protein?s sequence and its solubility, suggesting that mutational suppression of APRs could provide a simple strategy to increase protein solubility.
Some bacteria that live inside paramecia, which are tiny aquatic organisms, use a coiled protein ribbon that unfurls like a Chinese paper yo-yo to deliver a toxin to threatening organisms. The protein packs a punch, bursting through membranes of the paramecia's competitors as it elongates.
A researcher is making major progress on a first-of-its kind device to free kidney patients from dialysis. He is building an implantable artificial kidney with microchip filters and living kidney cells that will be powered by a patient?s own heart.