Despite the strong medical applications, the mechanism for telomerase holoenzyme (the most important unit of the telomerase complex) assembly remains poorly understood. New research provides, for the first time, an atomic level description of the protein-RNA interaction in the vertebrate telomerase complex.
Scientists have discovered a new relationship between the three-dimensional shape of the cell and its ability to migrate. The work has important implications for the fundamental understanding of cell movement and for practical applications like tissue engineering.
Researchers have reduced the sophisticated chemistry required for testing water safety to a simple pill, by adapting technology found in a dissolving breath strip. Want to know if a well is contaminated? Drop a pill in a vial of water and shake vigorously. If the colour changes, there's the answer.
The Strategic Vision represents the culmination of the strategic activities of the Synthetic Biology ERA-NET (ERASynBio) - a project which aims to develop and coordinate synthetic biology in the European Research Area.
Biotechnology scientists must be aware of the broad patent landscape and push for new patent and licensing guidelines, according to a new paper from Rice University's Baker Institute for Public Policy.
With gene expression analysis growing in importance for both basic researchers and medical practitioners, researchers at Carnegie Mellon University and the University of Maryland have developed a new computational method that dramatically speeds up estimates of gene activity from RNA sequencing data.
Shape-memory polymers are an important class of materials in medicine, especially for minimally invasive deployment of devices. However, the rate of translation of the concept to approved products is extremely low. A paper described the general usefulness as well as the limitations of the shape-memory polymers for biomedical applications.
A football-shaped structure, known as the mitotic spindle, makes cell division possible for many living things. This piece of cellular architecture, responsible for dividing up genetic material, is in constant flux. The filaments that form it grow and shrink, while motor-like molecules burn energy pushing them about. To ensure the complex process proceeds in an orderly fashion, molecular fasteners pin the filaments together in certain places, and new research helps explain how they do it.
Droplets of filamentous material enclosed in a lipid membrane: these are the models of a 'simplified' cell used by the SISSA physicists Luca Giomi and Antonio DeSimone, who simulated the spontaneous emergence of cell motility and division - that is, features of living material - in inanimate 'objects'.