Estimates suggest that biomedical research consumes almost a quarter of a trillion US dollars every year, yet according to some studies up to 85 per cent is avoidably wasted. Examples of waste include the non-publication of research, failure to share data and instances where the results of research are untranslatable to the benefit of patients or the efficiency of health care delivery.
Researchers describe a relatively accessible method for making a working - though not thinking - sphere of central nervous system tissue. The advance could provide an inexpensive and easy-to-make 3-D testbed for biomedical research.
Research by scientists has revealed important new information about the dynamics of bacterial gels which could ultimately suggest new ways of helping prevent or better control diseases such as cystic fibrosis.
The implantation of medical devices is not without risks. Bacterial or fungal infections can occur and the body's strong immune response may lead to the rejection of the implant. Researchers have succeeded in creating a biofilm with antimicrobial, antifungal and anti-inflammatory properties.
Scientists have developed a method for synthesising organic molecules very selectively, by assembling simple molecules and using an enzyme from E. coli , which acts as a biocatalyst. This is a significant step forward since it replicates the formation of carbohydrates in conditions resembling those that presumably initiated life on the Earth and because it allows relatively large organic molecules to be obtained very selectively and efficiently.