The new system - called BASIC - is a major advance for the field of synthetic biology, which designs and builds organisms able to make useful products such as medicines, energy, food, materials and chemicals.
Researchers examined the evolution origins of the D1 protein in cyanobacteria, which forms the heart of Photosystem II, the oxygen-evolving machine of photosynthesis. The research team selected all known D1 sequences from cyanobacteria and also representatives from algae and plants to compare the protein sequence variation.
Researchers used advanced proteomic techniques to identify 1,750 unique proteins in shoots of switchgrass, a native prairie grass viewed as one of the most promising of all the plants that could be used to produce advanced biofuels.
Researchers have successfully corrected a genetic error in stem cells from patients with sickle cell disease, and then used those cells to grow mature red blood cells. The study represents an important step toward more effectively treating certain patients with sickle cell disease who need frequent blood transfusions and currently have few options.
Researchers have created a 'heart-on-a-chip' that effectively uses human cardiac muscle cells derived from adult stem cells to model how a human heart reacts to cardiovascular medications. The system could one day replace animal models to screen for the safety and efficacy of new drugs.
After its success in the first joint call by ERASynBio, the collaborative project Synthetic Glycobiology - new strategies to build and functionalise proto-cells and proto-tissues is now set to receive roughly 1.9 million euros in total funding.
Modern biology has attained deep knowledge of how cells work, but the mechanisms by which cellular structures assemble and grow to the right size largely remain a mystery. Now, Princeton University researchers may have found the key in a dynamic agglomeration of molecules inside cells.