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Global genome effort seeks genetic roots of disease

By decoding the genomes of more than 1,000 people whose homelands stretch from Africa and Asia to Europe and the Americas, scientists have compiled the largest and most detailed catalog yet of human genetic variation. The massive resource will help medical researchers find the genetic roots of rare and common diseases in populations worldwide.

Oct 31st, 2012

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Cellular landscaping: Predicting how, and how fast, cells will change

A research team at the National Institute of Standards and Technology has developed a model for making quantifiable predictions of how a group of cells will react and change in response to a given environment or stimulus - and how quickly. The NIST model, in principle, makes it possible to assign reliable numbers to the complex evolution of a population of cells, a critical capability for efficient biomanufacturing as well as for the safety of stem cell-based therapies, among other applications.

Oct 31st, 2012

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Genome evolution and carbon dioxide dynamics

Using the size of guard cells in fossil plants to predict how much DNA each cell contained (the genome size), researchers have discovered that variations in genome sizes over geological time correlate with atmospheric carbon dioxide levels.

Oct 24th, 2012

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Evolution of new genes captured

Like job-seekers searching for a new position, living things sometimes have to pick up a new skill if they are going to succeed. Researchers from the University of California, Davis, and Uppsala University, Sweden, have shown for the first time how living organisms do this.

Oct 19th, 2012

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Virus exploits cellular waste disposal system

ETH-researchers demonstrate how vaccinia virus manipulates the cellular waste-disposal system and thereby cleverly tricks the cell into assisting the intruders replication. Now, the virologists have turned the tables, using inhibitors of this cellular waste-disposal system as a way to block virus infection.

Oct 18th, 2012

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Researchers develop new method for detection of specific DNA sequences

The detection of specific DNA sequences is central to the identification of disease-causing pathogens and genetic diseases, as well as other activities. But current detection technologies require amplification by polymerase chain reaction (PCR), fluorescent or enzymatic labels, and expensive instrumentation.

Oct 1st, 2012

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