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Nanotechnology Spotlights

New technique precisely determines nanoparticle uptake into individual cells

nanoparticles_inside_cellWhile nanoparticles are emerging as drug carriers for targeted nanomedicines, preclinical assays to test nanoparticle efficacy are hampered by the lack of methods to quantitatively determine internalized particles. A novel method is suited to pave the way for preclinical testing of nanoparticles to establish dose-efficacy relationships and to optimize biophysical and biochemical parameters in order to make better drug delivery...

Posted: Jun 18, 2013

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Destroying cancer cells by remote activation of intracellular nanoparticles

cancer_cellUnder an applied magnetic field, iron oxide nanoparticles trigger cancer cell death by bursting intracellular organelles. These findings offer a new strategy to treat cancer using nanomaterials. Researchers may be able to administer magnetic nanoparticles externally, allow them to accumulate at the tumor site, and then irradiate them with a magnetic field to induce cancer cell death. In the past, antibodies and small molecules...

Posted: Jun 14, 2013

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Capture and release of individual cancer cells with fractal nanostructures

fractal_nanostructureFractals are structures built up from repeated sizings of a simple shape to make a complex one. A fractal is a geometric structure that can repeat itself towards infinity. Zooming in on a fragment of it, the original structure becomes visible again. In biological systems, fractal structures can be found everywhere - bronchial trees, vasculature, and nerve cells. These amazing structures can provide a specific interfacial contact...

Posted: Jun 13, 2013

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How to design complex assemblies based on micelle-like nanostructures (w/video)

micelleOne major challenge in contemporary science is to accomplish with synthetic building blocks what nature does so well, that is, creating complex and functional structures through multiple levels of assembly of biomolecules. Bottom-up engineering of nanostructures that assemble themselves from polymer molecules are bound to become useful tools in chemistry. To that end, researchers are using block copolymer based micellar architectures...

Posted: Jun 12, 2013

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The physical basis of high-throughput atomically precise manufacturing

nanotechnologyAomically precise manufacturing (APM) can be understood through physics, engineering design principles, proof-of-concept examples, computational modeling, and parallels with familiar technologies. APM is a prospective production technology based on guiding the motion of reactive molecules to build progressively larger components and systems. Bottom-up atomic precision can enable production with unprecedented scope (in terms...

Posted: Jun 11, 2013

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Cheap nanotechnology paper-based gas sensors

Nanotechnology-enabled, paper-based sensors promise to be simple, portable, disposable, low power-consuming, and inexpensive sensor devices that will find ubiquitous use in medicine, detecting explosives, toxic substances, and environmental studies. Since monitoring needs for environmental, security, and medical purposes are growing fast, the demand for sensors that are low cost, low power-consuming, high sensitivity, and...

Posted: Jun 10, 2013

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Definition of the term 'nanomaterial'

nanomaterial_definitionIn order to regulate nanomaterials and to determine mandatory product labelling a generally accepted agreement what the term 'nanomaterial' means has to be reached beforehand. The EU Parliament requires that a definition shallbe science-based and comprehensive. Furthermore, for regulatory measures in individual sectors, it shall be unambiguous, flexible, easy and practical to handle. During the past few years various institutions...

Posted: Jun 06, 2013

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Flexible, carbon-based nanotechnology thin-film transistors

flexible_electronicsFlexible electronics are all the rage these days. They promise an entirely new design tool like for instance, tiny smartphones that wrap around our wrists, and flexible displays that fold out as newspapers or large as a television; or photovoltaic cells and reconfigurable antennas that conform to the roofs and trunks of our cars. This article reviews the progress in single-walled CNT and graphene-based flexible thin-film transistors...

Posted: Jun 05, 2013

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