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Researchers engineer 'protein switch' to dissect role of cancer's key players

Researchers at the University of North Carolina at Chapel Hill School of Medicine have 'rationally rewired' some of the cell's smallest components to create proteins that can be switched on or off by command. These 'protein switches' can be used to interrogate the inner workings of each cell, helping scientists uncover the molecular mechanisms of human health and disease.

Apr 10th, 2013

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Adult stem cells isolated from human intestinal tissue

The accomplishment provides a much-needed resource for scientists eager to uncover the true mechanisms of human stem cell biology. It also enables them to explore new tactics to treat inflammatory bowel disease or to ameliorate the side effects of chemotherapy and radiation, which often damage the gut.

Apr 5th, 2013

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DNA: how to unravel the tangle

A chromosome is rarely found in the shape we are used to seeing in biology books, that is to say the typical double rod shape. It is usually 'diluted' in the nucleus and creates a bundle that under the microscope appears as a messy tangle. A research coordinated by the scientists at SISSA of Trieste has now developed and studied a numeric model of the chromosome that supports the experimental data and provides a hypothesis on the bundle's function.

Mar 29th, 2013

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Biological transistor enables computing within living cells

A team of Stanford University bioengineers has taken computing beyond mechanics and electronics into the living realm of biology. They detail a biological transistor made from genetic material - DNA and RNA - in place of gears or electrons. The team calls its biological transistor the 'transcriptor'.

Mar 28th, 2013

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How does nanotechnology work?