Showing Spotlights 1409 - 1416 of 2140 in category (newest first):
Reciprocating devices are a common part of the macroscopic world. Examples of reciprocating machines are petrol and diesel engines or a hydraulic pump. At the core of these machines is a piston and cylinder assembly where the piston executes a reciprocating motion inside the cylinder. Reciprocating motion like that in a piston has not been available in a nanoscale machine until now. Ned Seeman and his team at New York University have designed a DNA device that exhibits reciprocal motion. They have used the PX-JX2 device, a robust sequence-dependent nanomechanical DNA machine, as the basis for constructing a pair of reciprocal devices, wherein one device assumes one state, while the other device assumes the opposite state.
Jun 11th, 2009
Molecular-size motors have evolved in nature, where they are used in virtually every important biological process. In contrast, the development of synthetic nanomotors that mimic the function of these amazing natural systems and that could be used in man-made nanodevices is in its infancy. Building nanoscale motors is not just an exercise in scaling down the design of a macroworld engine to nanoscale dimensions. In addition to organic molecules, scientists increasingly are looking to DNA as a very promising way to fabricate nanomotors. The concept of a single DNA molecule nanomotor was already introduced in early 2002. However, this and subsequent designs require addition and removal of fuel and waste strands for motor function, although some artificial nanomotors can utilize alternative energy sources, including hydrolysis of the DNA backbone and ATP. Researchers at the University of Florida have now designed a photoswitchable single-molecule DNA nanomotor. It is the first fully reversible single-molecule DNA nanomachine driven by photons without any additional DNA strands as fuel.
Jun 10th, 2009
The importance of novel markers for microcopy cannot be underestimated. Such markers can provide novel information about functioning of protein in cell. Owing to their unlimited photostability diamond nanoparticles can be used for long-term monitoring of intracellular processes. Diamond nanoparticles also appear to be ideal candidates for ultra microscopy techniques like STED. Furthermore, nitrogen-vacancy color centers in diamond have non-zero spin in the ground state. This allows their use as markers for magnetic resonance imaging with very high sensitivity. To date, few methods exist to produce diamond nanoparticles containing color centers (c-diamond), but they are only laboratory-scale. The most common, large-scale nanodiamond production method, detonation, produces diamond nanoparticles which do not contain any color centers but impurities such as surface-or lattice-aggregated nitrogen and metals in significant amounts. A German-French research team has now developed a high yield method for the large-scale production of fluorescent nanodiamonds.
Jun 9th, 2009
In a previous Spotlight we wrote about the fact that the environmental footprint created by today's nanomanufacturing technologies are conflicting with the general perception that nanotechnology is 'green' and clean. Adding to these concerns, a new study looks at the waste solids generated by the production of metallofullerenes and fullerenes and addresses the question whether feedstock-associated metals pose potential risks to aquatic receptors. The intent of this new study was to communicate that the purity of nanomaterials should be heavily characterized to ensure that the toxicological ramifications of the actual finished nanoproduct is accurately represented. Additionally, the authors suggest that carbon nanomanufacturing byproducts should be characterized so as to facilitate more informed decision-making on management of their associated waste streams.
Jun 8th, 2009
The fight against infections is as old as civilization. Silver, for instance, had already been recognized in ancient Greece and Rome for its infection-fighting properties and it has a long and intriguing history as an antibiotic in human health care. Modern day pharmaceutical companies developed powerful antibiotics - which also happen to be much more profitable than just plain old silver - an apparent high-tech solution to get nasty microbes such as harmful bacteria under control. However, thanks to emerging nanotechnology applications, silver is making a comeback in the form of antimicrobial nanoparticle coatings. As even the most powerful antibiotics become less and less effective, researchers have begun to re-evaluate old antimicrobial substances such as silver and as a result, antimicrobial nano-silver applications have become a very popular early commercial nanotechnology product. Researchers in China have now further advanced the nanotechnology application of silver be developing a novel multi-action nanofiber membrane containing four active components, each playing a different role in the membrane's excellent antibacterial function.
Jun 2nd, 2009
Increasing the efficiencies of polymer-based solar cells while at the same time keeping production complexity and cost low will require the preparation of new classes of polymers that can be prepared with a minimum of synthetic steps. Combining strong electron acceptors such as fullerenes (C60) with commodity polymers to make electronically active polymers promises to be one possible route. So far, though, the photovoltaic efficiencies of polymer/C60 blends are generally not as good as those for photovoltaic devices made from the currently used main classes of polymers, P3HT and PCBM. Researchers in France came up with a way to very simply prepare polymers from fullerenes without having to strongly change the aromaticity of the C60 sphere. This means that many of the original properties of C60 may be found to be retained even when combined with the beneficial properties of polymers.
May 29th, 2009
Theoretical studies have long predicted that the exceptional physical and chemical properties of a rigid monatomic linear chain of carbon atoms could function as the component of molecular devices, for instance in nanoelectronics. The problem has been that there was no reliable and effective way to produce these carbon chains and therefore scientists couldn't study them experimentally. While linear carbon chains have been already prepared either in solution or by vaporizing graphite, researchers in Japan have for the first time succeeded to derive the carbon atomic chains from graphene in a well controlled manner. This approach to realize freestanding carbon atomic chains employs energetic electron irradiation inside a transmission electron microscope.
May 28th, 2009
In a recent Nanowerk Spotlight we reported on a single molecule approach to directly visualize and map protein binding sites on DNA using fluorescent quantum dots. One of the challenges the researchers in this work had was to measure distances between probes bound to combed DNA with nanometer resolution. Whereas very short distance (below 10 nm) can be assessed by FRET measurements and distances above the Rayleigh criterion can be measured, say, with a standard microscopy picture and a ruler, distances in between need to be addressed differently. This is were a novel approach by scientists at UCLA fills the gap, and, as they claim, better than other techniques do.
May 27th, 2009