Showing Spotlights 1 - 8 of 99 in category Microscopy, Spectroscopy, Imaging (newest first):
Nanoparticles have shown a lot of promise in biomedical applications. However, accumulation of nanoparticles in the liver is a major concern, and may be one of the greatest barriers to the widespread adoption of nanoparticles in the clinic. This is especially true for metallic nanoparticles, since the long-term effects of their accumulation in the liver has not been widely studied.
A team of researchers has looked to nature for inspiration in solving this problem. They decided to use biliverdin, a bile pigment, as the building block for their nanoparticles.
Nov 18th, 2019
By precisely stacking various 2D materials in a predetermined sequence on top of each other, researchers create van der Waals heterostructures that, due to their unique interlayer coupling, have special optoelectronic properties. Unfortunately, the study of 2D monolayers is plagued by trapped contaminants in between the 2D sheets as well as between the 2D sheets and the underlying substrate. These contaminants make it difficult to obtain precise and reproducible experimental observations. A simple technique for removing these contaminants in a process similar to a squeegee.
May 1st, 2018
Among the important parameters in optical lithography is the spatial resolution you can get and the time you need to draw your pattern. Systems with regular and fixed patterns can be extremely fast but those systems are based on masks. Mask production is a time consuming and expensive process. So-called mask-less systems can draw unorganized patterns directly on substrates, at the cost of longer process times. Researchers now have presented a new lithographic approach with a high-resolution, low-cost technique based on nanosphere lithography.
Oct 4th, 2017
Photothermal induced resonance (PTIR) has found application in the characterization of materials in fields spanning from photovoltaics, plasmonic, polymer science, biology and geology to name a few. PTIR combines the spatial resolution of atomic force microscopy with the specificity of absorption spectroscopy, enabling mapping of composition and electronic bandgap, material identification and biomolecule conformational analysis with nanoscale spatial resolution. Scientists have now implemented, for the first time, an integrated near-field cavity-optomechanics readout concept to realize fully functional nanoscale AFM probes capable of ultralow detection noise within an extremely wide measurement bandwidth in ambient conditions, surpassing all previous AFM probes.
Sep 1st, 2017
Modern-day electronics or communication technology would not exist without electron microscopy, and the same can be said for many other types of technology. Beyond imaging, the focused beam of electrons is also used for analysis of the chemical composition, the crystal structure, and many other useful things. In new work, researchers have proposed to use graphene as a two-dimensional vacuum chamber, and build a two-dimensional electron microscope, where the electrons fly from the electron gun to the target without ever leaving the graphene sheet.
Jun 9th, 2017
Caenorhabditis elegans, a free-living soil nematode, has become an important experimental model for biomedical research. This nematode has been successfully employed in genetics, ageing research, behavioral assays, drug screening and (nano)toxicology. In a new study, researchers report for the first time the effective imaging of the nanoscale structure of C. elegans nematodes' cuticle using atomic force microscopy operating in PeakForce Tapping mode. This mode allows imaging C. elegans nematodes both in air and in their native liquid environment.
Nov 16th, 2016
Over the past few decades, the development of electron microscopy has gone hand in hand with techniques for atomically precise fabrication of 3D structures based on electron and ion beams. A recent review article illustrates the use of focused electron and ion beams (e-beams and i-beams) to induce highly localized chemical reactions at solid-vapor and solid-liquid interfaces, amorphous to crystalline phase transformations with atomic layer precision, and the motion of specific single dopant atoms within crystal lattices, thus laying the foundation for atomically precise directed assembly of materials and devices.
May 31st, 2016
The drawbacks of existing measures for calibrating scanning probe microscopes (SPMs) based on various diffraction gratings and periodic microstructures, are large period and large error of period. Both factors prevent using these measures for precise calibration of SPMs and other instruments operating in the nanometer range. To address this issue, researchers have developed a method of calibration of a scanning probe microscope by lattice constant of a crystal.
Mar 25th, 2016