Nanotechnology Spotlight – Latest Articles

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Showing Spotlights 1 - 8 of 437 in category Bionanotechnology, Nanomedicine (newest first):

 

Magnetically levitating proteins to precisely measure their density

levitating-proteinsThe density of proteins in solution is an important fundamental biophysical quantity that has not been accurately measured yet. This has led to extensive debate in the literature regarding the precise density value of proteins. This rough density metric can often lead to inaccurate estimates on the other physicochemical and composite protein features, especially after their interactions with other materials such as nanoparticles. Researchers have now demonstrated a new technique using superparamagnetic iron oxide nanoparticles for magnetic levitation, which promises a more precisely measurement of the density of proteins in solution.

Jan 13th, 2020

Metal-organic-framework-derived 2D carbon nanosheets for localized bacterial eradication and anti-infective therapy

mofThe combination of multiple therapeutic modalities with synergetic effects is a promising approach to enhance antibacterial efficiency and possibly decrease the needed concentration of bactericidal reagents. In new work, scientists report a path to achieve efficient localized bacterial eradication and anti-infective therapy by combining the advantages of 2D graphene and metal organic framework (MOF)-derived carbon nanomaterials. This proposed MOF-derived 2D carbon nanosheets (2D-CNs) can form aggregations spontaneously under NIR irradiation and meanwhile exhibit localized triple bactericidal modalities.

Jan 2nd, 2020

Living biosensors and micromotors as platform for precision medicine

microparticlesOptical biosensors and micromotors that can sense and actuate biological environments are considered promising theranostic devices because of their high spatial resolution and flexibility. Advancing the field from synthetic sensors to living materials - which often can be incompatible with biological systems - researchers have assembled living biosensors and micromotors using an in vivo red blood cell (RBC) waveguide for applications in pH sensing and particle transport. This living biosensor can be used for the diagnosis of pH-related disorders of the blood; then, the waveguide can rotate as a micromotor and transport microparticles to the target region.

Dec 16th, 2019

Nanotechnology could be good for your heart

heart-tissueAmong the various therapeutic advances, regenerative medicine and nanotechnologies have demonstrated a considerable capacity to salvage or regenerate damaged heart tissue in animal models. The superior characteristics of nanobiomaterials have shown great promise in developing engineered cardiovascular constructs for a variety of tissue engineering applications. But in order to develop efficient nanotechnology-based regenerative medicine platforms in humans, clinicians and engineers must achieve a greater common understanding of the problems, challenges, and opportunities in both fields.

Sep 10th, 2019

Pre-coating liposomes with an artificial protein corona reduces capture by immune system

protein-coronaDespite considerable, decade-long efforts in the field of nanomedicine, fewer nanoparticle technologies than expected have made it to clinical trials. Understanding the role of the nano-bio interface - the protein corona - appears to be a critical factor for successful clinical translation of medical nanotechnologies. New research demonstrates that the protein corona controls the interaction of liposomes with immune cells and reveals that the pre-coating of liposomes with an artificial corona made of human plasma proteins significantly decreases capture by circulating leukocytes in whole blood.

Aug 21st, 2019

Jellyfish-based nanofiber/nanoparticle wound dressing

jellyfishResearchers demonstrate the ease of use of jellyfish biomass as a biodegradable and biocompatible raw material for producing antibacterial mats. They report the successful electrospun-based preparation of novel composite biocompatible nanofibers based on jellyfish biomass. The antibacterial properties of the resulting nanofiber mats were enhanced by incorporating silver nanoparticles within applying an in situ bio-template synthesis that the team developed. This work suggests exploiting the jellyfish as an accessible, cheap and valuable renewable material that can be used in various applications, such as cosmetics, wound dressings, artificial skin, and bioplastics.

Jul 30th, 2019

Microwave dynamic therapy as a novel, effective cancer treatment

supernanoparticleResearchers have for the first time proposed a novel tumor treatment strategy for microwave dynamic therapy to effectively treat cancers. This technique can promote the efficacy of dynamic treatment of deep tumors in clinical research and could have a broad range of applications. The team found that liquid metal supernanoparticles can generate reactive oxygen species (ROS) under microwave irradiation. That makes them suitable as microwave sensitizers for revolutionizing the ROS generation techniques.

Jul 25th, 2019

Curcumin halloysite nanoformulation with selective antimicrobial effects

nanotubeTurmeric has a long history of usage in traditional medicine in India and China. Ancient Indians have known the medicinal properties of turmeric - i.e. curcumin - for several millennia. Researchers have now investigated the antibacterial effects of curcumin loaded into halloysite nanotubes and found that this nanoformulation drastically increased the life expectancy of nematodes infected by pathogenic bacteria. The most interesting finding here is the selective antimicrobial action of curcumin, which suppressed one bacterial species, while demonstrating no adverse effect on another.

Jul 15th, 2019