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New research reveals that the fundamental processes driven by copper are consistent across both inflammation and cancer metastasis. This newfound understanding of the influence of copper on cellular plasticity may pave the way for innovative therapeutic strategies in the future.
Scientists have developed an unprecedented artificial intelligence-driven tool that can predict the immune responses of human immune cells (specifically peripheral blood mononuclear cells) when they encounter nucleic acid nanoparticles or other therapeutic nucleic acids.
Scientists have designed a novel biocatalyst as an artificial antioxidase to improve stem cell transplantation outcomes and offers an efficient, multifaceted, and robust artificial antioxidase for broad-spectrum ROS scavenging and has the potential to enhance stem cell-related therapies and address various ROS-mediated diseases.
Researchers have developed an effective nanomedicine for catalytic ROS-scavenging and ultrafast healing of inflammatory wounds. This groundbreaking work holds the potential to pave the way for developing artificial biocatalysts to treat chronic inflammatory diseases, ultimately improving the lives of millions of diabetic patients worldwide.
A timely review covers the current state of protein corona research in nanomedicine, highlights challenges in research methodology and characterization, and discusses the role of artificial intelligence in advancing the field.
RNA nanotechnology is an emerging field that combines the unique properties of RNA with the principles of nanotechnology to create new and innovative applications in medicine, biotechnology, and materials science. Here we give an overview of RNA's potential in drug delivery, diagnostics, vaccine development and gene therapy.
Nanotechnology has the ability to completely transform the health care sector, particularly in developing countries like South Africa, where access to effective healthcare is still a challenge for millions of people living in poverty-stricken environments. Many African countries, despite having policies and strategies in place, struggle to allocate sufficient resources for research in nanomedicine. Most of the research conducted on the subject in Africa is focused on academic interests, rather than practical applications.
Its significance of the protein corona for biomedical applications lies in its role of imparting a unique biological identity to the nanoparticle, which could be very different from the pristine nanoparticle surface. Robust characterization of the identity and abundance of the protein corona is entirely dependent on liquid chromatography coupled to mass spectroscopy. Unfortunately, the variability of this technique for the purpose of protein corona characterization remains poorly understood.