Single-atom catalysts (SACs) have emerged as a new frontier in heterogeneous catalysis, and demonstrated distinguishing performances for various reactions due to their high catalytic activity with a significantly reduced amount of metals used. However, the catalytic performance of SACs for nitrogen fixation and conversion has been rarely explored. Scientists now have proposed a quite promising single-atom-based electrocatalyst for N2 reduction to NH3 under ambient conditions.
Researchers have demonstrated a novel approach toward smart orthodontics based on near-infrared red light from a mechanically flexible LED powered by flexible bio-safe batteries all integrated in a single 3D-printed dental brace. Integration of electronic devices in 3D printed dental aligners is a pragmatic approach towards implementing a flexible electronic technology in personalized advanced healthcare, particularly in orthodontics. Key to this smart brace is the use of a high-performance flexible solid-state microbattery.
The remarkable properties of some natural materials have motivated many researchers to synthesize biomimetic nanocomposites and other nanostructured materials that attempt to reproduce Nature's achievements. Recent research has indicated that the amplification of natural materials' mechanical properties far beyond those of the components that comprise them originates mainly from: 1) a hierarchical micro-/nanoscale architecture and 2) abundant effective interface interactions. A new progress report provides insight into the development of bio-inspired structural materials.
The crucial roles of the physicochemical properties of cell culture substrates on function and behavior of a wide range of the cells are becoming well-studied in the current literature, using experimental approaches. However, development of in silico approaches for prediction of cell responses to the physicochemical properties of substrates is still in its infancy. In new work, an international team of researchers has developed a unifying computational framework to create a multi-component virtual cell model to probe cell function/behavior in silico.
Researchers explore cellular uptake, endocytic pathways, and intracellular dynamics of nanoparticles in HeLa cells, both in absence and presence of biomolecular corona from human plasma. They find that the biomolecular corona could act as a personalized 'endogenous trigger' affecting off-target interactions and controlling the indication for disease of clinically approved formulations. Mechanistic investigations of the biomolecular corona could contribute to a better understanding of the poor success of targeted liposomal technology.
Notwithstanding the progress neuroscientists have made in understanding the microscale function of single neurons and the macroscale activity of the human brain - a comprehensive understanding of the brain still remains an elusive goal. Here we review the basic concepts associated with neuroscience and the current journey of nanotechnology towards the study of neuron function by addressing various concerns on the significant role of nanomaterials in neuroscience and by describing the future applications of this emerging technology.
Nanotechnology materials are going to open new realms of possibility for flexible and stretchable monitoring gadgets that are wearable directly on the skin. Here we look at the latest developments in a class of electronic devices, commonly referred to as electronic skin, epidermal electronics, or electronic tattoos, from the materials, devices, and medical applications perspectives. While such devices can also be used for prosthetics and rehabilitation, optogenetics, and human-machine interfaces, this review focuses on the properties of the materials that enable skin-mounted sensors for use as diagnostic tools in the medical field.
In order to fully exploit the potential of neural interfaces, the forthcoming generation of devices is expected to simultaneously offer multiple functionalities, including recording and stimulation of electrical activity, recognition of neurotransmitters, neuromodulators and other neurologically relevant biomolecules, as well as the capability for controlled drug delivery. Graphene and other 2D materials possess an array of properties (flexibility, electrical mobility, large surface area available for interaction with the neuronal components and amenable to surface modifications) that can enable enhanced functional capabilities for neural interfaces.