One way to eliminate the toxicity issue of synthetic nanomaterials used in nanomedicine is by working with truly biocompatible natural carriers for sensing and drug delivery applications. The emerging field of DNA nanotechnology may provide a solution. In new work, researchers have developed a novel theranostic platform which is made by utilizing a self-assembled DNA nanopyramid as scaffold for incorporation of both detection and therapeutic moieties to combat bacterial infection.
Industrial production processes, by and large, rely on robotic assembly lines that place, package, and connect a variety of disparate components. While the manufacturing world is dominated by robots, there are applications where the established processes of serial 'pick and place' and manipulation of single objects reach scaling limits in terms of throughput, alignment precision, and the minimal component dimension they can handle effectively. By contrast, the emerging methods of engineered self-assembly are massively parallel and have the potential to overcome these scaling limitations.
On September 15-16, 2014, come explore ways in which Alternative Testing Strategies (ATS) may be combined to create a Weight of Evidence (WOE) or 'multiple models' approach to inform context-specific decisions about risk from exposure to novel nanoscale materials. The goal is to advance a common understanding of the state of the science, early lessons, current opportunities, and next steps for developing ATS for use in decision making for nanoscale materials.
Many nanofabrication techniques depend on creating a structure on one substrate and then transferring it via various processes onto another, desired, substrate. Often, these methods are not generally applicable as they suffer from the process-specific drawbacks, such as for instance intolerance of transferred nanostructures to chemical etchant, and the harsh thermal environment needed. A novel universal and rapid method allows transferring nanostructures with various dimensions onto diverse substrates with high fidelity.
Thermoelectric materials hold great promise for turning waste heat back into useful power and are touted for use in hybrid cars, new and efficient refrigerators, and other cooling or heating applications. But they have one big drawback: they are very inefficient. Since thermoelectric devices work by maintaining a temperature difference between their different sides, it is important that the used materials have low conductivity, i.e. are good thermal insulators.
Defined as a clouding of the lens of the eye, cataracts affect more than 20 million people worldwide and accounts for 51 per cent of world blindness. In fact, this debilitating eye disease has been identified as the leading cause of blindness today. A multidisciplinary team of researchers is busy trying to understand the fundamental mechanisms of how the aggregates that cause cataracts form, and how nanotechnology may be used to prevent or at least inhibit them.
Cellular functions within living organisms are extremely complex processes and researchers have been using nanopatterned substrates to control and monitor cellular functions in order to design and fabricate nanoscale biotechnological systems. Especially stem cell research has benefitted from nanopatterned surfaces. Nevertheless, despite the intense scientific efforts to achieve precise control of stem cell fates with engineered nanopatterned substrates, reliable and cost effective control of stem cell behavior remains a challenge. Researchers have now fabricated biomimetic substrates that are similar to that of the native extracellular matrix in the epidermis which assists proliferation, differentiation, and biosynthesis of the keratinocyte (i.e. human outer skin) cells.
The microstructures of carbon nanotube assemblies determine their properties, for example, highly graphitized CNTs exhibit excellent mechanical and electrical properties; while CNTs with defects and poor crystallinity are beneficial for research on field emission property and hydrogen storage capacity. Therefore, it is of vital importance to control the CNT microstructures effectively for desired applications. A new technique can solve a problem of three-dimensional orientation control of CNTs in microscopic scale.