On September 15-16, 2014, come explore ways in which Alternative Testing Strategies (ATS) may be combined to create a Weight of Evidence (WOE) or 'multiple models' approach to inform context-specific decisions about risk from exposure to novel nanoscale materials. The goal is to advance a common understanding of the state of the science, early lessons, current opportunities, and next steps for developing ATS for use in decision making for nanoscale materials.
Defined as a clouding of the lens of the eye, cataracts affect more than 20 million people worldwide and accounts for 51 per cent of world blindness. In fact, this debilitating eye disease has been identified as the leading cause of blindness today. A multidisciplinary team of researchers is busy trying to understand the fundamental mechanisms of how the aggregates that cause cataracts form, and how nanotechnology may be used to prevent or at least inhibit them.
Concern about the depletion of global water resources has grown rapidly in the past decade due to our increasing global population and growing demand for other diverse applications. Since only 2.5% of the Earth's water is fresh, it has been reported that almost half of the world's population is at risk of a water crisis by the year 2025. Accordingly, significant research efforts have been focused on the desalination of brackish/seawater and the remediation and reuse of wastewater to meet the agricultural, industrial, and domestic water demands.
The desire to identify materials and their properties to understand complex systems and better engineer their functions has been driving scanning probe microscopies since their inception. Both atomic force microscopy (AFM) and Raman spectroscopy are techniques used to gather information about the surface properties and chemical information of a sample. There are many reasons to combine these two technologies, and this application note discusses both the complementary information gained from the techniques and how a researcher having access to a combined system can benefit from the additional information available.
More serious than the common cold, influenza viral infection has been responsible for major epidemics and pandemic respiratory disease in communities around the world. These epidemics come with substantial morbidity and mortality, accounting for 250,000 to 500,000 worldwide deaths each year and are particularly dangerous for vulnerable and elderly populations with statistics showing that 90% of those who succumb to the severe illness are 65 years and older. The flu is also associated with high health care costs. In the U.S., more than $80 billion dollars is spent annually as a result of influenza epidemics.
Surface metrology and characterization is ever more critical for overall product performance in wide ranging applications across the semi-conductor, LED, data storage, medical and automotive industries. 3D optical microscopes are among the fastest and most accurate imaging systems on the market today, and are employed in these industries for rapid and precise process monitoring, product development, and research. However, there are instances where they have performance limitations and the benefits of scanning probe/atomic force microscopy provide a clear advantage.
Ingenuity Lab in Edmonton, Alberta are taking cues from nature, as they focus on nanotechnology gains in the area of biomining. Using microorganisms and biomolecules, the group is making significant advances in the recovery of rare earth and precious metals from industrial processes and the environment thanks to superior molecular recognition techniques. The researchers at Alberta's first nanotechnology accelerator laboratory are looking to take advantage of inorganic binding peptides for mining valuable and rare earth elements/metals that exist in nature or synthetic materials.
Measuring and mapping mechanical properties of live cells is of high importance in today's biological research. raditionally, force spectroscopy and force volume are the most commonly used modes to quantitatively measure mechanical forces at the nanometer scale. Unfortunately, both techniques have suffered from slow acquisition speed and a lack of automated tools to analyze the hundreds to thousands of curves required for good statistics. This application note reviews recent progress in mapping the properties of soft samples such as cells and gels with force volume and PeakForce QNM and the use of the newest NanoScope and NanoScope Analysis features to collect and analyze the data from these techniques.