A new computational approach allows to account for confounding factors and hidden biological processes in the analysis of single-cell RNA sequence data. Using this method, individual subpopulations and cell types can be identified within heterogeneous cell populations and can be determined more precisely.
Striving to unravel and comprehend DNA's biological significance, scientists have created a new computational method that can identify positions in the human genome that play a role in the proper functioning of cells.
Scientists have devised a new strategy for selectively delivering genes into the mitochondria of plant cells by using a simple combination of cell-penetrating and mitochondria-targeting peptides. This work lays the groundwork for the rational design of peptide-based gene carriers with the potential to create a new field of 'mitochondria engineering', which could enable the creation of mitochondria-based plant cell factories for the creation of bio-polymers and bio-fuels.
Researchers have succeeded for the first time in amplifying gene samples containing DNA adducts while retaining references to these adducts. This type of amplification is a prerequisite for the majority of technologies used by researchers to determine a gene's DNA sequence.
New therapies are on the horizon for individuals paralyzed following spinal cord injury - the e-Dura implant developed by EPFL scientists can be applied directly to the spinal cord without causing damage and inflammation.
Scientists reveal a new technique that focuses diffuse light inside a dynamic scattering medium containing living tissue. In addition, they have improved the speed of optical focusing deep inside tissue by two orders of magnitude.