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Machine learning lets scientists reverse-engineer cellular control networks

Researchers used machine learning on a supercomputer to model the cellular control network that determines how tadpoles develop. Using that model, they reverse-engineered a drug intervention that created tadpoles with a form of mixed pigmentation never before seen in nature. They plan to use the method for cancer therapies and regenerative medicine.

Mar 23rd, 2017

Researchers grow heart tissue on spinach leaves (w/video)

Researchers turn to the vascular system of plants to solve a major bioengineering problem blocking the regeneration of human tissues and organs.

Mar 23rd, 2017

Combating wear and tear

Bioengineers detect early signs of damage in connective tissues such as ligaments, tendons and cartilage.

Mar 22nd, 2017

Single-cell analysis pave way for more accurate cancer prognosis

For the first time, researchers have applied single-cell transcriptomics to colorectal cancer (CRC) and discovered that this method could lead to improved patient stratification and eventually, a more accurate prognosis of CRC patients.

Mar 21st, 2017

Researchers explore a new method to study cholesterol distribution on cells

Findings could eventually help identify mechanisms linking cholesterol to coronary artery disease.

Mar 21st, 2017

Study points a way to better implants

Selectively blocking immune cells can prevent formation of scar tissue around medical devices.

Mar 20th, 2017

Rabbits' detached retina 'glued' with new hydrogel

A newly developed elastic gel administered in liquid form and shown to turn jellylike within minutes after injection into rabbits' eyes to replace the clear gelatinous fluid inside their eyeballs, may help pave the way for new eye surgery techniques.

Mar 20th, 2017

Bioengineered tooth restoration in a large mammal

The approach used involves the autologous transplantation of bioengineered tooth germ into a canine jawbone; the in vivo artificially created tooth has the structure, composition and physiological characteristics of a natural tooth.

Mar 20th, 2017

Computer simulation of protein synthesis reveals awesome complexity of cell machinery

The model system, based on E. coli, contained the bare minimum for assembling proteins: 241 chemicals undergoing 968 reactions for 1,000 seconds. Many of these chemicals twice reached steady concentrations, only to be suddenly depleted at a later stage.

Mar 16th, 2017

From skin to brain: Stem cells without genetic modification

New study yields neural crest cells from adult skin cells, and could lead to new treatments for Parkinson's and other brain illnesses.

Mar 16th, 2017

When proteins court each other, the dance moves matter

On the biological dance floor, careful choreography may decide how well a suitor is able to woo a partner.

Mar 16th, 2017

Protein dosage compensation mechanism unravelled

Scientists have discovered which genes from the yeast genome exhibit dosage compensation - the ability to temper protein production when the corresponding encoding gene's copy number increases. In addition, they identify the underlying process to be protein degradation, and link the mechanism to stoichiometric buffering of protein complex subunits.