Scientists have been able to reproduce, for the first time in human cells, chromosomal translocations associated with two types of cancer: acute myeloid leukemia and Ewing's sarcoma. The discovery opens the door to the development of new therapeutic targets to fight these types of cancer.
Scientists have discovered how a molecular 'scaffold' which allows key parts of cells to interact, comes apart in dementia and motor neuron disease, revealing a potential new target for drug discovery.
Like exploring the inner workings of a clock, a team of researchers is digging into the inner workings of the tiny cellular machines called spliceosomes, which help make all of the proteins our bodies need to function. In a recent study, they have captured images of this machine, revealing details never seen before.
The impact of the environment on our genetic makeup has long been a topic of discussion among researchers. Now a European consortium (EURATRANS) has taken the opposite approach. The scientists have investigated for the first time to what extent specific genetic predispositions influence the processes of gene regulation.
The gap between stem cell research and regenerative medicine just became a lot narrower, thanks to a new technique that coaxes stem cells to take the first step to specialization for the first time in a laboratory. Researchers demonstrated that not only is it possible for mouse embryonic stem cells to form three distinct germ layers in the lab, but also that it requires correct timing, chemical factors and mechanical environment.
Pioneering 'tweezers' that use ultrasound beams to grip and manipulate tiny clusters of cells under electronic, push-button control could lead to life-changing medical advances, such as better cartilage implants that reduce the need for knee replacement operations.
A new technology under development at the Georgia Institute of Technology could one day provide more efficient delivery of the bone regenerating growth factors with greater accuracy and at a lower cost.
Researchers have developed the first mobile application for Android phones that analyses ab1 DNA sequencing files, which enables science professionals and amateur enthusiasts to engage in scientific analysis on the go, from the convenience of their mobile phones.
Researchers demonstrate that the technique may be used to visualise 3D specimens up to 34 tomographic sections in depth. These new results compare well with sectioned images collected from a confocal microscope but have the added advantage of strong phase contrast, which removes the need for sample labelling or staining.