Using cryo-electron microscopy (cryo-EM), scientists have made a significant breakthrough in our understanding of how our molecular machinery finds the right DNA to copy, showing with unprecedented detail the role of a powerhouse transcription factor known as TFIID.
Scientists develop novel way to inject healthy human nerve cells into the brain. The technology involves converting adult tissue-derived stem cells into human neurons on 3-D scaffolds, or tiny islands, of fibers.
Scientists have developed a 3D micro-scaffold technology that promotes reprogramming of stem cells into neurons, and supports growth of neuronal connections capable of transmitting electrical signals. The injection of these networks of functioning human neural cells - compared to injecting individual cells - dramatically improved their survival following transplantation into mouse brains.
Remember those colorful 'grow capsules' that blossom into animal-shaped sponges in water? Using a similar idea, scientists have developed biodegradable polymer grafts that, when surgically placed in damaged vertebrae, should grow to be just the right size and shape to fix the spinal column.
Researchers recently demonstrated the design of softwood lignin-based polymers with potential application as alternatives to petroleum-based polystyrene. These softwood materials can be obtained from sources such as pine, cedar, spruce, and cypress trees.
Scientists have for the first time shown that it is possible to derive from a human embryo so-called 'na´ve' pluripotent stem cells - one of the most flexible types of stem cell, which can develop into all human tissue other than the placenta.
Researchers have created a hydrogel scaffold replicating the environment found within the human breast. The scaffold supports the growth of human mammary tissue from patient-derived cells and can be used to study normal breast development as well as breast cancer initiation and progression.