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Microfluidic vortex flows spur advances in robust cellular bioreactors

Directing microfluidic vortex flows to deposit recombinant E. coli cells as surface-adhered biofilms creates a new class of highly resilient, self-regenerative bioreactors for scalable biomaterial production.

January 31, 2024 Read more

Groundbreaking genome editing tools unlock new possibilities for precision medicine

Scientists developed a cutting-edge method that combines the power of designer-recombinases with programmable DNA-binding domains to create precise and adaptable genome editing tools.

January 31, 2024 Read more

DNA particles that mimic viruses hold promise as vaccines

Using a DNA-based scaffold carrying viral proteins, researchers created a vaccine that provokes a strong antibody response against SARS-CoV-2.

January 30, 2024 Read more

Harnessing cellular scaffolding for microscopic railways in nanotechnology and medicine (w/video)

Researchers harness the gossamer scaffolding that maintains the structure of living cells and used it to develop a nanotechnology platform. The technique eventually could lead to advances in soft robotics, new medicines, and the development of synthetic systems for high-precision biomolecular transport.

January 25, 2024 Read more

Breakthrough in muscle regeneration uses MXene scaffolds to support tissue growth

Researchers uncover molecular mechanisms behind the effects of MXene nanoparticles on muscle regeneration.

January 25, 2024 Read more

mRNA therapeutic successfully combats ovarian cancer in mice

The majority of high-grade ovarian cancers involve mutations in the p53 tumor suppressor gene, crucial for DNA repair and cell regulation. Researchers now developed a synthetic mRNA that successfully produced functional p53 protein in laboratory conditions, showing promise in cancer cell lines.

January 24, 2024 Read more

Delivering mRNA into the brain using lipid nanoparticles

Researchers devised a method to deliver mRNA into the brain using lipid nanoparticles, potentially advancing treatments for Alzheimer's disease and seizures.

January 24, 2024 Read more

Scientists unravel key steps in the road to DNA repair

Insights into homologous recombination (HR) promise new insights into cancer.

January 20, 2024 Read more

Machine learning techniques accelerate development of anti-inflammatory biomaterials

Researchers demonstrate how machine learning models can predict anti-inflammatory potential of polymers, enabling faster design of immunomodulatory biomaterials for medical implants.

January 20, 2024 Read more

Using DNA origami to show how an important cell receptor can be activated in a previously unknown way

The result opens new avenues for understanding how the Notch signalling pathway works and how it is involved in several serious diseases.

January 19, 2024 Read more

Nanopores and deep learning change disease diagnostics

Scientists unveil a groundbreaking method using biological nanopores and deep learning to detect protein modifications, offering new avenues in disease diagnostics.

January 18, 2024 Read more

Nanotechnology uncovering the hidden secrets of cancer

The European consortium 3DSecret is approaching metastasis in a new way, focusing on single cells and aiming to uncover hidden patterns that can predict and forecast how cancer spreads.

January 18, 2024 Read more

AI-based algorithm enables better genetic diagnoses

Scientists developed the AI-based algorithm STIGMA, which enables better diagnoses of congenital diseases. Several new disease genes have already been identified.

January 17, 2024 Read more

Researchers observe what ubiquitination hinges on

The flexibility of a protein hinge plays a crucial role in the transfer of proteins in key cell processes.

January 17, 2024 Read more

Tracking molecules at turbo speed

Scientists devise method to speed up observations of high-throughput microbiological process.

January 15, 2024 Read more

Observing single protein with infrared nanospectroscopy

The achievement represents a major advancement towards technological innovations such as ultra-sensitive and super-resolution infrared imaging, as well as single-molecule vibrational spectroscopy.

January 10, 2024 Read more

Microscopic ion trackers herald new era for organelle communication research

Combining pH nanosensors and super-resolution microscopy illuminates transient signaling between cellular organelles, unlocking new vistas for diagnosing and manipulating inter-organelle crosstalk.

January 5, 2024 Read more

On-demand conformation of an artificial cytoskeleton

Researchers presented a novel kind of cyclic peptide that, when light-irradiated, induces the formation or dissociation of nanotubes on demand.

January 3, 2024 Read more