Showing Spotlights 1905 - 1912 of 2340 in category All (newest first):
Slowly but surely the realization begins to sink in that there is no quick buck to be made for individual investors in nanotechnology companies (except for the people pushing investment advice of course). Existing public nanotechnology firms as a group have performed sub-standard (to put it politely); there isn't exactly a flood of nanotech IPOs on the horizon; and many product advances that have to do with nanotechnologies are made by large companies which either make these advances silently (witness the cosmetics industry) or tout them as major breakthroughs (like IBM's 'airgap' technology). In any case, all these nanotechnology-based materials are incremental improvements over existing materials - leading to better coatings, more efficient batteries and fuel cells, better performing materials, etc. - and not revolutionary devices. Of course, when we look back 10 years from now, there will have been one or two great performing nanotech stocks (I will tell you in 2017 who they are); but then there will be one or two great performing stocks in almost any other investment sector. Nevertheless, there are many start-ups and early stage companies out there - some might even make it to the IPO (initial public offering) stage or be bought by larger companies - and given the nature of the field, with its broad and multidisciplinary character, it certainly is helpful for the professional investor to be able to gauge the nanotechnology investment landscape from a technology perspective. A recent article describes a methodology to categorize different nanotechnologies into one of three types: passive, active, or hybrid nanotechnologies, each with different time horizons for expected commercial viability.
Nov 14th, 2007
Fundamental nanotechnology research in laboratories advances rapidly, as witnessed by the hundreds of new research papers that get published every month. The big bottleneck in getting these new technologies from the lab translated into commercial products is the lack of suitable large-scale fabrication techniques. Almost all laboratory experiments involve elaborate set-ups and are quite tricky processes that require a lot of skill and expertise on part of the researchers. To a large degree, nanotechnology today is more an art than a basis for industrial technologies. Think about a 15th century monk spending 10 years painstakingly writing and painting a single bible - that's where nanotechnology is today; but where we need to get to is something that resembles modern high speed printing machines where you print thousands of books an hour. Take for instance nanowires. Researchers have used nanowires to create transistors like those used in memory devices and prototype sensors for gases or biomolecules. A common approach in the lab is to grow nanowires like blades of grass on a suitable substrate, mow them off and mix them in a fluid to transfer them to a test surface, using some method to give them a preferred orientation. When the carrier fluid dries, the nanowires are left behind like tumbled jackstraws. Using scanning probe microscopy or similar tools, researchers hunt around for a convenient, isolated nanowire to work on, or place electrical contacts without knowing the exact positions of the nanowires. It's not a technique suitable for mass production. However, researchers have now developed a technique that allows them to selectively grow nanowires on sapphire wafers in specific positions and orientations accurately enough to attach contacts and layer other circuit elements, all with conventional lithography techniques. This fabrication method requires a minimum number of steps and is compatible with today's microelectronics industry.
Nov 13th, 2007
Some pundits writing about nanotechnology get carried away by their own hype and talk about self-assembly as if bottom-up fabrication technologies, where molecules get assembled into everyday products, are just around the corner. We took a swing at this in our Spotlight from a few days ago (Nanotechnology 'pencil sharpeners' add to researchers' nanofabrication toolbox). Today we bring you another example from the cold reality of the labs that makes clear how early stages this whole field of self-assembly really is. Today, when researchers - with both feet firmly on the ground - talk about self-assembly they mostly talk about template-assisted nanocrystal superlattices in the form of planar thin films. Bottomline is that even the controllable fabrication of highly ordered homogeneous nanostructures on surfaces remains a difficult challenge. And IBM's much touted 'self-assembling nanotechnology' (see: IBM applies self-assembling nanotechnology to conventional chip manufacturing) is nothing more than a patterning process that creates a film with trillions of holes around the on-chip wiring. Moving from a planar geometry of self-assembled nanoscale building blocks such as nanocrystals or nanotubes to a free-standing, three-dimensional multifunctional architecture is not a trivial undertaking. Researchers are just about to make the first steps to such multifunctional (still nanoscale) hierarchical architectures that both retain the properties of the nanocrystals and offer multifunctionality.
Nov 12th, 2007
Nanofluidic channels, confining and transporting tiny amounts of fluid, are the pipelines that make the cellular activities of organisms possible. Nanoscale channels carry nutrients into cells and waste from cells and they also transport water into and out of the cell. Body temperature, digestion, reproduction, fluid pressure in the eye, and water conservation in the kidney are only a few of the processes in humans that depend on the proper functioning of cellular water channels. Special proteins called aquaporins can transport water through the cell membrane at a high rate while effectively blocking everything else - even individual protons, the nuclei of hydrogen atoms. The aquaporin channels are so narrow that no molecule larger than water can pass through, effectively forcing them through like beads on a chain. A unique distribution of amino acid residues along the pore wall also accounts for the channel's ability to move water quickly. To keep out molecules smaller than water there is also a chemical filter, formed by the specific orientation and distribution of the amino acid residues lining the pore. Thus water, and only water, flows freely through the aquaporin nanochannels, the direction of flow depending only on changing relative pressure inside and outside the cell. This intriguing mechanism has attracted the attention of nanotechnology researchers who see it as a blueprint for the construction of nanoscale water pumps. A molecular dynamics simulation conducted by Chinese researchers proposes a design for such a molecular pump constructed with a carbon nanotube.
Nov 9th, 2007
Titanium oxide - due to its versatile optical, electrical and photochemical properties, its relative abundance and low cost, and its non-toxicity - is an important ceramic material with numerous applications as pigments; powders for catalytic or photocatalytic applications; colloids and thin films for photovoltaic, electrochromic, photochromic, electroluminescence devices and sensors; components for antireflecting coatings; or porous membranes for ultrafiltration. Nanocrystalline titania has become a prominent material for dye-sensitized solar cells (DSSCs, also known as 'Grätzel cells' after their inventor), which are photoelectrochemical cells that use photo-sensitization of wide-band-gap mesoporous oxide semiconductors. One major problem with the use of titania in solar cells is that its bandgap does not match that of visible light and titania therefore can only absorb 3-4% of the energy from sunlight. Grätzel cells decrease the bandgap of titania by using dye-absorbed TiO2 nanocrystals as one of the electrodes, resulting in a higher solar energy conversion of 10% or more. Other methods use doping and indeed the application of nitrogen-doped titania as photocatalyst has received increasing attention over the last years because N-doping is found to be particularly effective in decreasing the bandgap of anatase (many of the properties of titania depend on the structure of the TiO2 phase - mainly anatase, brookite and rutile). In order for photocatalysis-based applications to become commercially viable, it will be critical to design low-cost, reproducible, synthetic methods that yield controlled, reproducible, and easy-to-handle nanomaterials processed as coatings with high surface area and high porosity. Researchers in France and Spain now describe for the first time nanostructured coatings that fulfill all these requirements.
Nov 8th, 2007
Nanotechnology's poster child, the carbon nanotube (CNT), has been explored for use in many technical applications. Increasingly, researchers are also looking at the unique biological properties of CNTs for potential biomedical uses. For instance, the interaction between DNA and CNTs have been explored and DNA-functionalized nanotubes hold significant promise as nucleic acid sensors. Nanotubes have also been considered for use as scaffolds for cells in tissue engineering. No matter what their intended function, any material used in medicine must exhibit - among other compatibility factors - biocompatibility, non-toxicity and non-carcinogenicity. And here the jury is still out as far as CNTs are concerned. One limiting factor of toxicological studies so far has been the use of animal tissue rather than living specimen. Researchers have now succeeded in detecting single-walled CNTs (SWCNTs) inside living animals - with surprisingly benign results - paving the way for future research on the effects and fate of nanotubes inside living organisms.
Nov 7th, 2007
Proteins, large organic compounds made of amino acids, provide many of the most basic units of function in living systems. They make up about half of the dry mass of animals and humans. There may be as many as 1 million different types of proteins in the human body (it is estimated that the human proteome is comprised of an average of 5-7 protein isoforms per open reading frame in the human genome and a further 600 000-odd immunoglobulins present in serum at any given moment) - nobody really knows. The word protein comes from the Greek prota, meaning 'of primary importance', and they actually may become of great importance in nanoscale fabrication as well. Proteins have an amazing number of functions inside our bodies: Enzymes serve as catalysts to break down food into various components; transport proteins such as hemoglobin transport molecules (e.g. oxygen); storage proteins store molecules (e.g. iron is stored in the liver as a complex with the protein ferritin); structural proteins such as keratin or collagen are needed for mechanical support in tissues like cartilage and skin but also hair and nails; proteins are the major component of muscles and for instance actin or myosin are key to contracting muscle fibers; hormones control the growth of cells and their differentiation; antibody proteins are needed for immune protection; and toxins are, well, toxic, but in minute amounts could have beneficial medical properties. Scientists believe that this variety of natural protein functions - actuation, catalysis, structural transport and molecular sequestering - could serve as valuable and versatile building blocks for synthesis of functional materials. Researchers now have found that nanometer-scale changes in protein conformation can be translated into macroscopic changes in material properties. The result is a new class of dynamic, protein-based materials.
Nov 6th, 2007
Animals that cling to walls and walk on ceilings owe this ability to micro- and nanoscale attachment elements. The highest adhesion forces are encountered in geckos. For centuries, the ability of geckos to climb any vertical surface or hang from ceilings with one toe has always generated considerable interest. A gecko is the heaviest animal that can 'stand' on a ceiling, with its feet over its head. This is why scientists are intensely researching the adhesive system of the tiny hairs on its feet. On the sole of a gecko's toes there are some one billion tiny adhesive hairs called setae (3-130 micrometers in length), splitting into even smaller spatulae (about 200 nanometers in both width and length) at the end. It was found that these elastic hairs induce strong van der Waals forces. This finding has prompted many researchers to use synthetic microarrays to mimic gecko feet. Recent work, mainly from A. Dhinojwala, P.M. Ajayan, M. Meyyappan, and L. Dai groups, as well as the Max Planck Institute for Metals Research in Germany (see our previous Spotlight: Gecko nanotechnology), has indicated that aligned carbon nanotubes (CNTs) sticking out of substrate surfaces showed strong nanometer-scale adhesion forces. Although carbon nanotubes are thousands of times thinner than a human hair, they can be stronger than steel, lighter than plastic, more conductive than copper for electricity and diamond for heat. Applications of such bio-inspired development of artificial dry adhesive systems with aligned carbon nanotubes could range from low-tech fridge magnets to holding together electronics or even airplane parts.
Nov 5th, 2007