Miniaturizing traditional laboratory assays to automated lab-on-a-chip devices holds tremendous potential for enabling multiplex, efficient, cost-effective and accurate pathogen sensing systems for both security and medical applications. These sensors could be used to detect bacteria such as E. coli and Salmonella, but also other pathogens that could be used for bioterrorism. Traditional identification methods required time intensive cell culturing processes but novel pathogen sensors based on nanomaterials are promising vastly improved and speedy detection technologies. A recent example is a label-free sensor chip assembled from peptide nanotubes that enables the electrical detection of viruses with an extremely low detection limit. This could lead to compact super-sensitive pathogen detection chips for point of care applications that have a high tolerance against false-positive signals.
Advances in micro- and nanoscale engineering have led to various mobile devices that either can move on solids or swim in fluids. Researchers are applying various strategies to designing nanoscale propulsion systems by either using or copying biological systems such as the flagellar motors of bacteria or by employing various chemical reactions. Many of these approaches are fairly complex and not necessarily suited for large-scale deployment in practical applications. Scientists have theorized about simpler designs for mechanical swimmers that avoid the complexities of biological mechanisms and use very few degrees of freedom.
Researchers in Spain have now demonstrated the experimental realization of a simple device made by microscopic colloidal particles which can be externally controlled and propelled at low Reynolds number condition, i.e. when the viscosity of the fluid dominates over the inertia of the object. This is the same condition that governs the motion of bacteria such as E. Coli or other micro- or nanoscale objects that move in a fluid.
Nanotechnology researchers are actively working on the beginnings of various nanorobotic systems that one day could lead to automated, assembly-line type nanofabrication processes. Last year we reported on a nanogripper, a kind of a robotic 'hand' some ten thousand times smaller than a human hand. This 'pick-and-place' device used a silicon gripper which was controlled by a nanorobotic arm and was capable of picking up a carbon nanofiber and fix it onto the tip of an atomic force microscope cantilever. One of the problems that is vexing researchers is that the nanoscale miniaturization of these grippers comes at the cost of reduced strength - the smaller the gripper, the weaker it becomes. Therefore what is needed is a gripper design that is strong enough yet sufficient flexible and small to handle tough materials like carbon nanotubes.
Experiments with graphene have revealed some fascinating phenomena that excite researchers who are working towards molecular electronics. It was found that graphene remains capable of conducting electricity even at the limit of nominally zero carrier concentration because the electrons don't seem to slow down or localize. This means that graphene never stops conducting. Taking advantage of the conducting properties of graphene, researchers now have described how graphene memory could potentially be used as a new type of memory that could significantly exceed the performance of current state-of-the-art flash memory technology. Their results show the possibility to build next-generation memory devices with vast amounts of memory using nanocables with a silicon dioxide core and a shell of stacked sheets of graphene.
The UK's Royal Commission on Environmental Pollution in a new report clearly states that it found no evidence of harm to health or the environment from nanomaterials but it believes that the pace at which such new nanomaterials are being developed and marketed is beyond the capacity of existing testing and regulatory arrangements to control the potential environmental impacts adequately. A major conclusion of the report is that nanomaterials are hugely variable in their nature. They are not a uniform class of materials, and attempts to regulate or legislate solely on the basis of their size or how they are made are misguided. It is the functionality of nanomaterials, i.e. what they do and how they behave, that matters and this should form the basis of governance and regulation. The report makes a number of recommendations on how to deal with ignorance and uncertainty in the area of nanomaterials, which could also be applied to other areas of fast-paced technological development.
When the U.S. military talks about space superiority it defines this as the degree of control necessary to employ, maneuver, and engage space forces while denying the same capability to an adversary. Although 'space forces' has a Star Wars ring to it, the term basically refers to satellites and these satellites - at least as far as unclassified information goes - do not carry weapons (yet); although the public website of the U.S. Air Force Space Command in listing its capabilities mentions the ability to conduct defensive and offensive counterspace operations, and space environment assessments. The main functions of the military's space capabilities today are information related - weather, communications, surveillance, reconnaissance, navigation and missile warning capabilities - and has become critical to many military operations. As other military powers build up their space programs, defensive and offensive space capabilities become more of an issue for war planers - something they call counterspace activities.
Titanium dioxide nanoparticles have become a commercially significant nanomaterial and are being used in products around the world - in cosmetics and sunscreen lotions, paint formulations, coatings, self-cleaning additives, even in antibacterial applications. The increased use of nanomaterials such as titania goes hand in hand with a growing number of reports on the risks associated with these materials, which have arisen because insufficient information has been gathered about their reactivity and stability once they leave the laboratory. Unfortunately, pinpointing every conceivable situation that nanoparticles could interact in is an enormous multi-parameter problem and solving this by experimental testing alone is not feasible due to the huge numbers of combinatorial variations. This is where theoretical predictions can help, by rapidly and systematically sampling possibilities, and highlighting where experimentalists should focus their attention.
Shrinking device size to nanometer dimensions presents many fascinating opportunities such as manipulating nano objects with nanotools, measuring mass in attogram ranges, sensing forces at femtonewton scales, and inducing gigahertz motion, among other new possibilities waiting to be discovered. The two principal components common to most electromechanical systems irrespective of scale are a mechanical element and transducers. The mechanical element either deflects or vibrates in response to an applied force. Depending on their type, the mechanical elements can be used to sense static or time-varying forces. The transducers in microelectromechanical systems (MEMS) and nanoelectromechanical systems (NEMS) convert mechanical energy into electrical or optical signals and vice versa. A Spanish team has now demonstrated an ultrasensitive carbon nanotube based mass sensor in which they measured chromium atoms with a mass resolution of only 1.4 zeptograms.